A brief review of some of the cases of knowledge & technology being lost across history, (EG library of Alexandria) and why this is a significant threat with a rapidly advancing technological landscape. An overview of some of the biology that underlies human development & learning, and how this affects the mentorship landscape. An examination of different developmental relationships that rely on a mentorship-like relationship, focusing on highlighting key lessons from each. A practical step-by-step example of how these lessons have been and can be used in our own mentorship relationships.