As designers, we know achieving superior real world treatment outcomes requires more than just clinical results. We know that improving a person’s quality of life and fulfilling human needs are the forces which turn the barely-tolerable burden of medical management into something meaningful and integral to a person’s life.In this talk, the author details how the Novo Nordisk Devices and Delivery solutions team has continued to evolve its research and design operations over the 7 years with measurable results. The author introduces new or under-appreciated opportunities where experience design can evolve to shape more holistic treatment experiences. The talk concludes with a framework for using within healthcare organizations to evaluate their own journey in advancing human-centered design operations.